Efficacy of the preparation ANANDIN® 10 % for injection solution in respiratory and gastrointestinal diseases of pigs

The study objective was to investigate the therapeutic efficacy of the medicinal preparation for veterinary use ANANDIN® 10 % solution for injection (manufacturing organisation LLC “AVZ S-P”, Russia) in respiratory and gastrointestinal diseases of pigs. The test was carried out on 40 piglets of 2–2.5 months old Landrace and Large White breeds with symptoms of respiratory and gastrointestinal diseases, as well as metabolic disorders. Based on the results of clinical and laboratory tests, four experimental and one control groups of 8 piglets each were formed. The piglets of the experimental groups were administered the drug ANANDIN® 10 % solution for injection, and piglets of the control group were administered the antibiotic Amoxicillin 150. Based on the analysis of the results of clinical examination and haematological and biochemical studies of animals of experimental groups, immunostimulating, immunomodulatory efficacy and mediated anti-inflammatory effect of the drug were established. The tendency of modulating effect of the medicinal preparation ANANDIN® 10 % solution expressed in the decrease of the total number of leukocytes with the increase of the number of lymphocytes and segmented neutrophils up to physiological parameters was revealed. Reduction of erythrocyte sedimentation rate and a significant decrease in the total number of leukocytes confirms the stimulating effect of the studied immunomodulator on phagocytosis, macrophage activity of monocytes and, as a consequence, on the control of the inflammatory process in tissues and organs.