A phase I/II trial evaluating the safety of increased-dose S- 1 with oxaliplatin and nivolumab in HER2-negative advanced gastric cancer
This study was approved by the University of Tokyo Clinical Research Review Board (URL: https://www.ut-crescent.jp/patients/chiken_jisshi/ , review number: 2022529SP) and was initiated at 19 institutions in June 2023 (registered as jRCTs031230127).
Authors
- Toshihiro Kudo (ORCID: https://orcid.org/0000-0003-3584-6375)
- Yosuke Kito
- Hirokazu Shoji (ORCID: https://orcid.org/0000-0002-8922-5227)
- Kenro Tanoue (ORCID: https://orcid.org/0009-0005-0583-4412)
- Eishi Baba
- Eisuke Booka (ORCID: https://orcid.org/0009-0008-3856-1715)
- Chiyo K. Imamura (ORCID: https://orcid.org/0000-0003-2907-847X)
- Masashi Takeuchi (ORCID: https://orcid.org/0000-0003-3797-432X)
- Takuro Mizukami (ORCID: https://orcid.org/0000-0002-9960-5629)
- Yoshiyasu Kono (ORCID: https://orcid.org/0000-0002-4717-5196)
- Kengo Nagashima (ORCID: https://orcid.org/0000-0003-4529-9045)
- Hiroya Takeuchi (ORCID: https://orcid.org/0000-0002-3947-0128)
- Kei Saito (ORCID: https://orcid.org/0000-0002-5726-8775)
- Nobumi Suzuki (ORCID: https://orcid.org/0000-0001-9566-8828)
- Hirofumi Kawakubo (ORCID: https://orcid.org/0000-0002-4929-5482)
- Kanako Saito
- Daisuke Takahari (ORCID: https://orcid.org/0000-0002-2492-6014)
- Narikazu Boku
- Toshifumi Yamaguchi (ORCID: https://orcid.org/0000-0003-1399-1918)
- Takeshi Kawakami
- Keisuke Baba
- Chiyoe Kitagawa
- Takuya Tsunoda
- Keiji Ogura
- Shinzo Yamamoto
Institutions
- Nihon University (JP)
- SHOWA Medical University (JP)
- Kyushu University (JP)
- Okayama University (JP)
- Keio University (JP)
- NTT Medical Center (JP)
- Hamamatsu University School of Medicine (JP)
- Shizuoka Cancer Center (JP)
- Japanese Red Cross Medical Center (JP)
- Keio University Hospital (JP)
- University of Tokyo Hospital (JP)
- Mie University Hospital (JP)
- Ishikawa Prefectural Central Hospital (JP)
- The Cancer Institute Hospital (JP)
- National Cancer Center Hospital East (JP)
- Osaka International Cancer Institute (JP)
- Nagoya Medical Center (JP)
- Tokyo Metropolitan Police Hospital (JP)
- Japanese Foundation For Cancer Research (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1186/s12885-025-14084-1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nihon University
- Keio University
- Japan Society for the Promotion of Science
- Institute of Medical Science, University of Tokyo