Study of acute oral toxicity of the new drug «Amoxiyantar» on laboratory animals

One of the key studies, after pharmaceutical research, is toxicological studies, which determine the hazard class and lethal dose of the drug. We conducted a study, in the course of studying acute toxicity, to determine the average lethal dose and lethal dose of a new drug for veterinary use Amoxiyantar. When summarizing the results of the study of acute oral toxicity in mice, when testing doses of 7500 and 12 500 mg/kg, there were no signs of intoxication in experimental mice, and no animal deaths were recorded during the experiment. According to the results of a study of acute oral toxicity in rats, when testing a dose of 22 500 mg/kg, signs of intoxication were observed in experimental rats, the death of three animals from this group was recorded during the experiment, which can be considered this dose LD50. During the experiment, it was proved that a dose of 25 000 mg/kg is lethal LD100.