Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice
Collectively, our findings demonstrated activation of GPER1 alleviated WMI via modulating microglia M2 polarization after ICH through EGFR/Stat3 signaling pathway.
Authors
- Jun Zhong (ORCID: https://orcid.org/0000-0001-9553-0423)
- Hongfei Ge (ORCID: https://orcid.org/0000-0002-6232-2107)
- Jianchao Mao (ORCID: https://orcid.org/0000-0002-2616-6688)
- Huanhuan Li (ORCID: https://orcid.org/0000-0001-5260-6993)
- Chao Zhang (ORCID: https://orcid.org/0000-0001-8126-8145)
- Xuyang Zhang (ORCID: https://orcid.org/0000-0002-4665-3934)
Institutions
- Army Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- Journal of Stroke and Cerebrovascular Diseases
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108315
- Citations
- 1
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Chongqing Science and Technology Commission
- Natural Science Foundation of Chongqing
- Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission