AL amyloidosis with elevated peripheral blood cell counts – A frequent association with liver involvement. A single-center retrospective study

Elevated peripheral blood counts in a subset of patients with AL amyloidosis constitute a rare but significant phenomenon and appear to be associated with frequent hepatic involvement. We hypothesize that cytokine deregulation and hyposplenism may belong to its pathomechanisms.

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Publication Details

Journal
Leukemia Research Reports
Published
2025-01-01
DOI
https://doi.org/10.1016/j.lrr.2025.100509
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
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article
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article

AL amyloidosis with elevated peripheral blood cell counts – A frequent association with liver involvement. A single-center retrospective study

Mateusz Ziarkiewicz, Piotr Boguradzki, Krzysztof Jamroziak, Grzegorz Władysław Basak et al.
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Leukemia Research Reports
Amyloidosis: Diagnosis, Treatment, Outcomes
article

AL amyloidosis with elevated peripheral blood cell counts – A frequent association with liver involvement. A single-center retrospective study

Mateusz Ziarkiewicz, Piotr Boguradzki, Krzysztof Jamroziak, Grzegorz Władysław Basak, Marta Legatowicz-Koprowska, Joanna Ewa Drozd-Sokolowska, Justyna Szczygieł
article en

Abstract

Elevated peripheral blood counts in a subset of patients with AL amyloidosis constitute a rare but significant phenomenon and appear to be associated with frequent hepatic involvement. We hypothesize that cytokine deregulation and hyposplenism may belong to its pathomechanisms.

Leukemia Research ReportsVol. 23
Medical University of Warsaw (PL), National Institute of Geriatrics, Rheumatology and Rehabilitation (PL), Institute of Cardiology (PL)
Openalex Percentile: Top 93%
Amyloidosis: Diagnosis, Treatment, Outcomes
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