Added value of multi-parametric magnetic resonance imaging in prostate imaging reporting and data system for evaluation of prostatic cancer

Background The eighth most deadly cancer in men in 2020 was prostate cancer (PCa), which killed 375 304 men. One of the many applications of MRI is to help with biopsy selection and to make it easier to target lesions during the procedure directly. Staging tumor extent and monitoring treatment response are two more areas where it proves useful. The Prostate Imaging Reporting and Data System (PI-RADS) scoring system, in conjunction with multi-parametric MRI (mp-MRI), allowed for a more precise diagnosis of PCa. Aim To determine the efficacy of mp-MRI using the PI-RADS in the detection of PCa. Patients and methods Our study enrolled 52 cases suspected of having PCa, who were referred from the urology department at Urology and Nephrology Center, Faculty of Medicine, Mansoura University. Results Comparing benign and malignant lesions in this investigation, we found that PI-RADS and mp-MRI (T2, apparent diffusion coefficient, dynamic contrast, and diffusion weighted image) showed significantly different results ( P = 0.001* and (0.001*, 0.001*, 0,002*, and 0.001*), respectively). PI-RADS sensitivity was 93.55%, specificity was 66.67%, and accuracy 82.69%. Conclusions Applying the PI-RADS using mp-MRI added a higher significant value in PCa detection and evaluation, by a novel, noninvasive imaging tool with high sensitivity and accuracy.

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Publication Details

Journal
Tanta Medical Journal
Published
2025-04-01
DOI
https://doi.org/10.4103/tmj.tmj_89_24
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Added value of multi-parametric magnetic resonance imaging in prostate imaging reporting and data system for evaluation of prostatic cancer

Ahmed M. El-Sharkawy, Sameh Ahmed Khodair, Mohamed El‐Azab, Mona A.A. Eldsouky
1 links
Tanta Medical Journal
Prostate Cancer Diagnosis and Treatment
article

Added value of multi-parametric magnetic resonance imaging in prostate imaging reporting and data system for evaluation of prostatic cancer

Ahmed M. El-Sharkawy, Sameh Ahmed Khodair, Mohamed El‐Azab, Mona A.A. Eldsouky
article en

Abstract

Background The eighth most deadly cancer in men in 2020 was prostate cancer (PCa), which killed 375 304 men. One of the many applications of MRI is to help with biopsy selection and to make it easier to target lesions during the procedure directly. Staging tumor extent and monitoring treatment response are two more areas where it proves useful. The Prostate Imaging Reporting and Data System (PI-RADS) scoring system, in conjunction with multi-parametric MRI (mp-MRI), allowed for a more precise diagnosis of PCa. Aim To determine the efficacy of mp-MRI using the PI-RADS in the detection of PCa. Patients and methods Our study enrolled 52 cases suspected of having PCa, who were referred from the urology department at Urology and Nephrology Center, Faculty of Medicine, Mansoura University. Results Comparing benign and malignant lesions in this investigation, we found that PI-RADS and mp-MRI (T2, apparent diffusion coefficient, dynamic contrast, and diffusion weighted image) showed significantly different results ( P = 0.001* and (0.001*, 0.001*, 0,002*, and 0.001*), respectively). PI-RADS sensitivity was 93.55%, specificity was 66.67%, and accuracy 82.69%. Conclusions Applying the PI-RADS using mp-MRI added a higher significant value in PCa detection and evaluation, by a novel, noninvasive imaging tool with high sensitivity and accuracy.

Tanta Medical JournalVol. 53(2)
Mansoura University (EG), Tanta University Hospital (EG)
Openalex Percentile: Top 88%
Prostate Cancer Diagnosis and Treatment
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