The relationship between 1,25(OH) <sub>2</sub> D <sub>3</sub> levels and interleukin-32 and vascular endothelial growth factor levels in endometriosis cyst tissue: An original article
These findings underscore the role of active vitamin D in mitigating inflammation associated with endometriosis by reducing interleukin-32 and vascular endothelial growth factor, critical factors in inflammatory responses and blood vessel formation. Moreover, the positive association between vascular endothelial growth factor and interleukin-32 highlights their collaborative role in the inflammatory processes underlying endometriosis. This study contributes to understanding how vitamin D may modulate key inflammatory pathways implicated in the pathogenesis of this condition.
Authors
- Mulyanusa Amarullah Ritonga (ORCID: https://orcid.org/0000-0002-4323-7855)
- Hanom Husni Syam (ORCID: https://orcid.org/0000-0001-9799-5224)
- Shofwal Widad
- Anita Rachmawati (ORCID: https://orcid.org/0009-0008-4591-0223)
- Wiryawan Permadi (ORCID: https://orcid.org/0000-0002-3275-7521)
- Ruswana Anwar (ORCID: https://orcid.org/0000-0001-5416-1238)
- Mirza Ismail (ORCID: https://orcid.org/0000-0002-9994-7362)
Institutions
- Universitas Gadjah Mada (ID)
- Dr. Hasan Sadikin General Hospital (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- SAGE Open Medicine
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1177/20503121251332405
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Padjadjaran