Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

Results suggest that fetal exposure to an overall mixture of EDCs may be adversely associated with several biomarkers of male fecundity, but findings are also compatible with null associations. These associations, if true, appeared to be driven by PFAS, but misclassification due to a single measurement of the phthalate metabolites and triclosan may have attenuated the results.

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Publication Details

Journal
Andrology
Published
2025-04-12
DOI
https://doi.org/10.1111/andr.70039
Primary Topic
Effects and risks of endocrine disrupting chemicals
Type
article
Field-Weighted Citation Impact
0.00

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article

Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

Sandra Søgaard Tøttenborg, Cecilia Høst Ramlau‐Hansen, Zeyan Liew, Esben Meulengracht Flachs et al.
Andrology
Effects and risks of endocrine disrupting chemicals
article

Fetal exposure to a mixture of endocrine‐disrupting chemicals and biomarkers of male fecundity: A population‐based cohort study

Sandra Søgaard Tøttenborg, Cecilia Høst Ramlau‐Hansen, Zeyan Liew, Esben Meulengracht Flachs, Gunnar Toft, Sidsel Dan Hull, Karin Sørig ­Hougaard, Christian H. Lindh, Lauren Anne Wise, Allen J. Wilcox, Kajsa Kirstine Ugelvig Petersen, Jens ­Peter Bonde
article en

Abstract

Results suggest that fetal exposure to an overall mixture of EDCs may be adversely associated with several biomarkers of male fecundity, but findings are also compatible with null associations. These associations, if true, appeared to be driven by PFAS, but misclassification due to a single measurement of the phthalate metabolites and triclosan may have attenuated the results.

AndrologyVol. 14(1)
Boston University (US), University of Copenhagen (DK), Steno Diabetes Centers (DK), Lund University (SE), Aarhus University (DK), Frederiksberg Hospital (DK), Aarhus University Hospital (DK), Copenhagen University Hospital (DK), National Institute of Environmental Health Sciences (US), Yale New Haven Health System (US), National Research Centre for the Working Environment (DK)
Dagmar Marshalls Fond, European Commission, Ferring, Lundbeckfonden, Danmarks Frie Forskningsfond, Region Hovedstaden, A.P. Møller og Hustru Chastine Mc-Kinney Møllers Fond til almene Formaal, Helsefonden, Novo Nordisk Fonden, H. Lundbeck A/S
Openalex Percentile: Top 91%
Effects and risks of endocrine disrupting chemicals
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