Cardiological adverse events in hepatocellular carcinoma patients receiving immunotherapy: Influence of comorbidities and clinical outcomes
Comorbid conditions, particularly AHT and T2DM, amplify the risk of MACE and influence treatment discontinuation. The CARDIOSOR scale is a valuable tool for personalized risk assessment, guiding tailored therapeutic strategies. Integrating cardiovascular risk management into HCC care is crucial for optimizing both oncological and cardiovascular outcomes.
Authors
- Marco Sanduzzi‐Zamparelli (ORCID: https://orcid.org/0000-0003-3795-3705)
- Ferràn Torres (ORCID: https://orcid.org/0000-0002-7355-7913)
- Enric Cascos (ORCID: https://orcid.org/0000-0002-9093-3642)
- Andrés Castaño‐García (ORCID: https://orcid.org/0000-0002-7921-9026)
- Marı́a Varela (ORCID: https://orcid.org/0000-0003-4288-2593)
- Melina González
- Neus Llarch (ORCID: https://orcid.org/0000-0003-3209-0453)
- Gemma Iserte (ORCID: https://orcid.org/0000-0003-3908-8743)
- Ana María Piedra-Cerezal (ORCID: https://orcid.org/0000-0001-7715-1032)
- Marta García Calonge (ORCID: https://orcid.org/0000-0001-8817-9225)
- María Reig (ORCID: https://orcid.org/0000-0002-5711-9534)
- Rebeca Lorca (ORCID: https://orcid.org/0000-0002-7803-4011)
- Marta Fortuny (ORCID: https://orcid.org/0000-0003-4413-7909)
- Marta Campos
- Óscar Arrabal
- Manuel Rodríguez (ORCID: https://orcid.org/0000-0001-5763-7668)
- Alicia Mesa (ORCID: https://orcid.org/0009-0008-5470-7593)
- Aida Marsal
Institutions
- Universitat Autònoma de Barcelona (ES)
- Universidad de Oviedo (ES)
- Hospital Clínic de Barcelona (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Hospital Universitario Central de Asturias (ES)
- Instituto de Investigación Sanitaria del Principado de Asturias (ES)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.ejca.2025.115404
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Albert Einstein Cancer Center
- Asociación Española para el Estudio del Hígado
- Fundación Científica Asociación Española Contra el Cáncer
- Generalitat de Catalunya
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
- Societat Catalana de Digestologia
- Instituto de Salud Carlos III