Impact of hypoxic versus oxic conditions on local tumor control after proton irradiation in a rat prostate carcinoma
Proton irradiations showed a 5 % reduction in OER compared to the previously measured photon value of 1.53 ± 0.08, suggesting a slightly higher effectiveness of protons in hypoxic tumors as compared to photons.
Authors
- Stephan Brons (ORCID: https://orcid.org/0000-0002-4695-0816)
- Peter Peschke
- Michaela Schmitt
- Ina Kurth (ORCID: https://orcid.org/0000-0001-9261-5165)
- Christin Glowa (ORCID: https://orcid.org/0000-0002-5557-9799)
- Christian P. Karger (ORCID: https://orcid.org/0000-0002-7194-8136)
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Heidelberger Institut für Radioonkologie (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.ctro.2025.100957
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Krebsforschungszentrum
- Deutsche Forschungsgemeinschaft