Depressive symptoms partially mediate the relationship between psychosocial factors and epigenetic age acceleration in a multi-racial/ethnic sample of older adults
from this study may help elucidate the relationship between psychosocial factors and epigenetic aging, which is critical in understanding the biological mechanisms through which psychosocial factors may contribute to age-related disease.
Authors
- Lauren Opsasnick (ORCID: https://orcid.org/0000-0001-6345-7276)
- Lauren Schmitz (ORCID: https://orcid.org/0000-0002-1641-289X)
- Belinda L. Needham (ORCID: https://orcid.org/0000-0001-5939-2027)
- Xiang Zhou (ORCID: https://orcid.org/0000-0002-4331-7599)
- Scott M. Ratliff (ORCID: https://orcid.org/0000-0002-6109-662X)
- Jennifer A. Smith (ORCID: https://orcid.org/0000-0002-3575-5468)
- Wei Zhao (ORCID: https://orcid.org/0000-0001-7388-0692)
- Jessica D. Faul (ORCID: https://orcid.org/0000-0002-6969-6478)
Institutions
- Northwestern University (US)
- University of Wisconsin–Madison (US)
- University of Michigan (US)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.bbih.2025.100994
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Human Genome Research Institute