Image quality evaluation of imaging skins, a novel stretchable X-ray detector for intraoperative tumour imaging

This paper presents the development of a novel X-ray detector composed of silicone elastomer and GOS:Tb, which we refer to as imaging skins. These detectors were integrated into a custom X-ray system to convert radiation into visible light. Our study focused on how fabrication parameters such as thickness and concentration impact sensor linearity, considering their potential application directly on the skin or organs to identify tumour margins during surgery. In addition, we examined how the stretching capabilities of these detectors influenced the image quality. Our imaging detection stack demonstrated consistent linearity across various fabrication parameters with the coefficient of determination ([Formula: see text]) more than 0.99998, showing that the silicone elastomer does not affect the conversion of the X-ray into light. We achieved a spatial resolution of 1.16-1.42 lp/mm at 10% of the Spatial Frequency Response using a 0.5-mm thick sensor. This study represents a first step towards integrating stretchable X-ray detectors into clinical settings, particularly on curved surfaces, to unlock their full potential in complex surgical configurations. It also highlights the need for a deeper understanding of the interactions between X-rays and detector materials to fully interpret the observed effects.

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Publication Details

Journal
Scientific Reports
Published
2025-04-11
DOI
https://doi.org/10.1038/s41598-025-96768-z
Citations
1
Primary Topic
Optical Imaging and Spectroscopy Techniques
Type
article
Field-Weighted Citation Impact
1.36

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article

Image quality evaluation of imaging skins, a novel stretchable X-ray detector for intraoperative tumour imaging

Robert Moss, Agostino Stilli, Solène Dietsch, Lukas Lindenroth et al.
1 citations
Scientific Reports
Optical Imaging and Spectroscopy Techniques
1.36
article

Image quality evaluation of imaging skins, a novel stretchable X-ray detector for intraoperative tumour imaging

Robert Moss, Agostino Stilli, Solène Dietsch, Lukas Lindenroth, Danail Stoyanov, Harry Allan
article en
1 citations

Abstract

This paper presents the development of a novel X-ray detector composed of silicone elastomer and GOS:Tb, which we refer to as imaging skins. These detectors were integrated into a custom X-ray system to convert radiation into visible light. Our study focused on how fabrication parameters such as thickness and concentration impact sensor linearity, considering their potential application directly on the skin or organs to identify tumour margins during surgery. In addition, we examined how the stretching capabilities of these detectors influenced the image quality. Our imaging detection stack demonstrated consistent linearity across various fabrication parameters with the coefficient of determination ([Formula: see text]) more than 0.99998, showing that the silicone elastomer does not affect the conversion of the X-ray into light. We achieved a spatial resolution of 1.16-1.42 lp/mm at 10% of the Spatial Frequency Response using a 0.5-mm thick sensor. This study represents a first step towards integrating stretchable X-ray detectors into clinical settings, particularly on curved surfaces, to unlock their full potential in complex surgical configurations. It also highlights the need for a deeper understanding of the interactions between X-rays and detector materials to fully interpret the observed effects.

Scientific ReportsVol. 15(1)
King's College London (GB), The Francis Crick Institute (GB), Wellcome / EPSRC Centre for Interventional and Surgical Sciences (GB), University College London (GB)
Royal Academy of Engineering, Wellcome / EPSRC Centre for Interventional and Surgical Sciences, Engineering and Physical Sciences Research Council
Openalex Percentile: Top 21%
Optical Imaging and Spectroscopy Techniques
1.36
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