Delayed regional metastasis from small face/scalp cutaneous squamous carcinoma: outcomes and predictors

In our review, perineural invasion (PNI) was the one factor predictive of delayed regional lymph node metastasis. This observation confirms the use of PNI to upstage even small CSCC to T3. Prophylactic treatment of the neck in patients with small scalp/face cancers with PNI should be strongly considered, especially in the age of immunotherapy.

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Publication Details

Journal
Archives of Dermatological Research
Published
2025-04-12
DOI
https://doi.org/10.1007/s00403-025-04224-9
Citations
1
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
1.35
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article

Delayed regional metastasis from small face/scalp cutaneous squamous carcinoma: outcomes and predictors

John D. Boughter, Courtney B. Shires, Christopher Golembeski, Merry Sebelik et al.
1 citations
Archives of Dermatological Research
Nonmelanoma Skin Cancer Studies
1.35
article

Delayed regional metastasis from small face/scalp cutaneous squamous carcinoma: outcomes and predictors

John D. Boughter, Courtney B. Shires, Christopher Golembeski, Merry Sebelik, A Hall, N. C. Craig Sharp
article en
1 citations

Abstract

In our review, perineural invasion (PNI) was the one factor predictive of delayed regional lymph node metastasis. This observation confirms the use of PNI to upstage even small CSCC to T3. Prophylactic treatment of the neck in patients with small scalp/face cancers with PNI should be strongly considered, especially in the age of immunotherapy.

Archives of Dermatological ResearchVol. 317(1)
Baptist Memorial Hospital (US), Emory University (US), University of Tennessee Health Science Center (US), Samford University (US)
Zero hunger
Openalex Percentile: Top 21%
Nonmelanoma Skin Cancer Studies
1.35
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