Changing definitions of disease: Transformations in the diagnostic criteria for Alzheimer's disease
Early diagnosis and incorporating scientific insights are recurring aims. The aims of new criteria are often not clearly articulated or ambiguous. The number of requirements for an AD diagnosis decreases over time. Consecutive criteria for research and clinical use did not result in clear terminology. The AD definition is increasingly narrowed to amyloid β and tau.
Authors
- Edo Richard (ORCID: https://orcid.org/0000-0002-7250-3390)
- Harro van Lente (ORCID: https://orcid.org/0000-0002-4719-360X)
- Marianne Boenink (ORCID: https://orcid.org/0000-0002-7017-0043)
- Lennart H. van der Molen
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
- TropIQ Health Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/alz.70133
- Citations
- 5
- Primary Topic
- Mental Health and Psychiatry
- Type
- article
- Field-Weighted Citation Impact
- 86.33
Funders
- ZonMw