E2F1-driven EXOSC10 transcription promotes hepatocellular carcinoma growth and stemness: a potential therapeutic target
E2F1 promotes EXOSC10 transcription and then facilitates HCC growth and cancer stemness, revealing a potential target for HCC therapy.
Authors
- Xiaofeng Yuan (ORCID: https://orcid.org/0000-0002-4890-4813)
- Bing Leng (ORCID: https://orcid.org/0000-0001-8262-1852)
- Yanrui Zhang
- Lishi Xiao (ORCID: https://orcid.org/0000-0001-7917-0587)
- Jifei Liu (ORCID: https://orcid.org/0000-0002-7460-1939)
- Xiaolei Yu (ORCID: https://orcid.org/0000-0001-5941-9306)
- Yongpeng He (ORCID: https://orcid.org/0009-0009-6096-6935)
- Dingyong Wu
- Haoyue Deng
Institutions
- Suizhou Central Hospital (CN)
- Zhongshan Hospital (CN)
- Chongqing Cancer Hospital (CN)
- Jingning County People's Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1186/s41065-025-00430-7
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment