Glioblastoma with markedly reduced contrast enhancement after corticosteroid administration: Increased density and reduced diffusion capability are noteworthy
Corticosteroids are widely used to manage peritumoral edema and associated neurological deficits in patients with brain tumors. We describe the case of a 71-year-old male patient with glioblastoma in which contrast enhancement decreased on radiographic imaging following corticosteroid administration, which has been reported previously in only 9 cases. This report aims to discuss radiographic changes in glioblastoma (density on computed tomography and diffusion capability on diffusion-weighted magnetic resonance imaging, in addition to enhancement on contrast-enhanced T1-weighted magnetic resonance imaging) following steroid administration and also following steroid discontinuation.
Authors
- Hironori Haga (ORCID: https://orcid.org/0000-0003-4322-9561)
- Masahiro Tanji (ORCID: https://orcid.org/0009-0002-2459-1856)
- Satoshi Nakajima (ORCID: https://orcid.org/0000-0001-5088-4017)
- Yuji Nakamoto (ORCID: https://orcid.org/0000-0001-5783-8048)
- Yasuhide Takeuchi (ORCID: https://orcid.org/0000-0002-1262-2355)
- Yoshiki Arakawa (ORCID: https://orcid.org/0000-0003-4626-4645)
- Yasutaka Fushimi (ORCID: https://orcid.org/0000-0002-1982-3168)
- Yohei Mineharu (ORCID: https://orcid.org/0000-0002-6346-3999)
- Takaaki Kitano
- Daiki Toda
Institutions
- Kyoto University (JP)
- Kyoto University Hospital (JP)
Publication Details
- Journal
- Radiology Case Reports
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.radcr.2025.03.052
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.25