Сlinical and epidemiological features of sexually transmitted infections combined with other infections included in the list of socially significant diseases

The aim was to describe the clinical and epidemiological features of sexually transmitted infections (STIs) combined with other infections included in the list of socially significant diseases (SSIDs). Materials and methods. The research material was data published in scientific articles of domestic and foreign publications for the period from 2011 to 2023 on STI/SSID coinfection. Results and discussion. Based on the analyzed research results, the following aspects characterizing the features of STI/SSID coinfection were considered. Epidemiology features: 1) the predominance of the population from the risk groups is more represented in comparison with monoinfection; 2) a significant proportion of cases of their combination with STIs in the structure of various SSIDs. Clinical features (in comparison with monoinfection): 1) a more severe course of the infectious process due to the synergistic effect of two or more pathogens acting on the body simultaneously; 2) the presence of atypical clinical manifestations; 3) the predominance of rare localizations. Immunological features: 1) difficulties in conducting immunological diagnostics; 2) significant differences in immunological parameters when combined with various STIs. Prevention and treatment features: 1) high recurrence rate after treatment; 2) more complex routing of patients associated with the need for timely and coordinated work of physicians: infectiologists, dermatovenerologists, phthisiatricians. Conclusion. The clinical and epidemiological features of STIs combined with other infections included in the list of socially significant diseases necessitate the improvement of diagnosis, treatment, prevention, and monitoring of patients with this pathology