Research Progress of Imagingomics in Coronary CTA Evaluation of Vulnerable Plaques

When vulnerable plaques in the coronary artery are ruptured or corrosive, they can easily lead to the occurrence of acute coronary syndrome (ACS). Today, various intracoronary imaging technologies can be used to detect vulnerable plaques. Traditional coronary CT angiography (CCTA, hereinafter referred to as coronary CTA) is considered a first-line choice for risk stratification of cardiovascular disease and to evaluate stable or unstable plaques. However, it mainly relies on subjective visual evaluation of diagnostic physicians and is prone to ignore many important features of vulnerable plaques. Imaging omics extracts many imaging features that cannot be captured by the human body from coronary CTA, which can better analyze and judge vulnerable plaques. This paper mainly reviews the application of imagingomics to evaluate the characteristics of vulnerable plaques in coronary CTA and related heart disease and other imaging techniques for vulnerable plaques and related clinical risk events.