The Associations of Maternal Prepregnancy Body Mass Index With Human Milk Fatty Acid and Phospholipid Composition in the Observational Norwegian Human Milk Study
Biological factors likely increased stearoyl-CoA desaturase activity, lower lipoprotein lipase activity, and a compensatory higher contribution of nonesterified FA from adipose tissue in mothers with pBMI ≥30 could potentially lead to the observed outcomes. Metabolic differences regarding BMI variances may influence the FA availability for mammary gland triglyceride and PL synthesis. Therefore, in addition to dietary intake, maintaining a healthy maternal pBMI may improve the nutritional quality of human milk, ultimately supporting infants' development.
Authors
- Hans Demmelmair (ORCID: https://orcid.org/0000-0001-7812-5178)
- Merete Eggesbø (ORCID: https://orcid.org/0000-0002-0006-5336)
- Talat Bashir Ahmed
- Martina Totzauer (ORCID: https://orcid.org/0000-0002-8205-7785)
- Berthold V Koletzko (ORCID: https://orcid.org/0000-0002-5345-7165)
- Rachel Criswell
Institutions
- Lowell General Hospital (US)
- LMU Klinikum (DE)
- German Center for Pediatric and Adolescent Rheumatology (DE)
- Norwegian University of Life Sciences (NO)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Journal of Nutrition
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.tjnut.2025.04.009
- Citations
- 2
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- University Hospitals
- Bundesministerium für Bildung und Forschung
- Norges Forskningsråd