Tongfu Xingshen capsule alleviates stroke-associated pneumonia-induced multiple organ injuries by modulating the gut microbiota and sphingolipid metabolism
TFXS exerts anti-inflammatory and protective effects on the brain, lung, and gut by alleviating gut microbiota dysbiosis and sphingolipid metabolism disorders. These findings highlight TFXS as a promising therapeutic candidate for the treatment of SAP.
Authors
- Baoying Gong (ORCID: https://orcid.org/0000-0002-2874-4840)
- Zhenzhen Lou
- Ru Yan (ORCID: https://orcid.org/0000-0001-6268-360X)
- Juan Huang (ORCID: https://orcid.org/0000-0003-1477-2602)
- Jianwen Guo (ORCID: https://orcid.org/0009-0000-4120-7671)
- Changlian Gan
- D.H. Wang
- Geng Li (ORCID: https://orcid.org/0000-0002-2441-2427)
- Tianqin Xiong (ORCID: https://orcid.org/0000-0002-5996-0589)
- Ruihua Wang (ORCID: https://orcid.org/0000-0002-4020-8039)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangdong Pharmaceutical University (CN)
- University of Macau (MO)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-04-12
- DOI
- https://doi.org/10.1016/j.phymed.2025.156756
- Citations
- 4
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 3.22