Comparative evaluation of CAR-expressing T-, NK-, NKT-cells, and macrophages in an immunocompetent mouse glioma model
These data provide a valuable basis as to which immune cells can mediate effective anti-glioma response in an immuno-competent glioma environment. Our data also suggest that a combination of CAR-T and CAR-NKT-cells may represent a promising therapeutic strategy.
Authors
- Tiffany Chen (ORCID: https://orcid.org/0000-0003-2546-2941)
- Payal Watchmaker (ORCID: https://orcid.org/0000-0002-0944-3890)
- Psalm Pineo-Cavanaugh (ORCID: https://orcid.org/0000-0002-1521-1607)
- Su Phyu (ORCID: https://orcid.org/0000-0003-1775-6966)
- David H. Raulet (ORCID: https://orcid.org/0000-0002-1257-8649)
- Hideho Okada (ORCID: https://orcid.org/0000-0003-0076-9920)
- Keith Kyewalabye (ORCID: https://orcid.org/0000-0003-3645-6328)
- Yitzhar Goretsky
- Pavlina Chuntova (ORCID: https://orcid.org/0000-0002-5356-9909)
- Akane Yamamichi (ORCID: https://orcid.org/0000-0002-8141-7339)
- Ryusuke Hatae (ORCID: https://orcid.org/0000-0001-5636-8064)
- Marco Gallus (ORCID: https://orcid.org/0009-0007-4954-8420)
- Jeffrey Haegelin
- Masaki Terabe (ORCID: https://orcid.org/0000-0002-1777-0189)
- Kaori Okada
- Haoyu Long
- Lan Phung
Institutions
- National Institutes of Health (US)
- University of California, San Francisco (US)
- Parker Institute for Cancer Immunotherapy (US)
- National Cancer Institute (US)
- Neurological Surgery (US)
- Molecular Sciences Institute (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf074
- Citations
- 4
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Deutsche Forschungsgemeinschaft
- National Institutes of Health