Long-term remission of microsatellite instability-high adenosquamous carcinoma in gastric antrum: a case report
This case underscores the potential efficacy of integrating surgery, chemotherapy, and immunotherapy in managing gastric ASC, particularly in the context of MSI-H and elevated PD-L1 expression. It further emphasizes the critical role of comprehensive molecular profiling in guiding personalized therapeutic strategies for such rare malignancies. Further research and additional case reports are imperative to establish optimal management protocols for gastric ASC and to enhance long-term outcomes.
Authors
- Caiqiang Xue (ORCID: https://orcid.org/0000-0002-3117-0358)
- Qing Zhou (ORCID: https://orcid.org/0000-0002-4433-055X)
- Liu Yong-yong
- Peng Zhang (ORCID: https://orcid.org/0000-0002-8403-8289)
- H. J. Yang (ORCID: https://orcid.org/0009-0004-8274-9863)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-1529-6356)
- Yumin Li (ORCID: https://orcid.org/0000-0002-9267-1412)
Institutions
- Lanzhou University Second Hospital (CN)
- Sichuan Provincial Hospital of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Chengdu University of Traditional Chinese (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.3389/fonc.2025.1516966
- Primary Topic
- Colorectal and Anal Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00