Association between alactic base excess on mortality in sepsis patients: a retrospective observational study
ABE demonstrated a U-shaped association with 30-day and 90-day ICU all-cause mortality in critically ill sepsis patients, suggesting its superiority over BE and lactate as a predictive biomarker. Incorporating ABE with the SOFA score may further enhance prognostic predictions. Further studies are needed to determine whether ABE should serve solely as a biomarker for monitoring the clinical course or could also be considered a potential therapeutic target.
Authors
- Qiang Tong (ORCID: https://orcid.org/0000-0002-0179-9681)
- Bin Yang (ORCID: https://orcid.org/0000-0002-3944-8035)
- Yang Chen
- Yuan Yuan (ORCID: https://orcid.org/0000-0002-7394-9036)
- Kang Ye
- Jiabao Zhao (ORCID: https://orcid.org/0000-0002-0691-5741)
- Tianshu Ren
Institutions
- Shenyang Medical College (CN)
- University of Liverpool (GB)
- Liverpool Heart and Chest Hospital (GB)
- General Hospital of Shenyang Military Region (CN)
- Liverpool John Moores University (GB)
Publication Details
- Journal
- Journal of Intensive Care
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1186/s40560-025-00789-9
- Citations
- 9
- Primary Topic
- Renal function and acid-base balance
- Type
- article
- Field-Weighted Citation Impact
- 12.88