Oligoadenylate synthetase-like aggravated Newcastle disease virus–induced necroptosis in glioma cells

Our study demonstrates that NDV has cytolytic activity on glioma cells by inducing necroptosis. Additionally, targeting upregulation of OASL may provide a novel strategy to enhance necrotic apoptosis in glioma cells after NDV infection.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-04-11
DOI
https://doi.org/10.3389/fonc.2025.1574214
Citations
4
Primary Topic
interferon and immune responses
Type
article
Field-Weighted Citation Impact
3.19
Controls
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article

Oligoadenylate synthetase-like aggravated Newcastle disease virus–induced necroptosis in glioma cells

Yangkun Chen, Wei Han, Wenjing Ye, Fangwei Dai et al.
4 citations
Frontiers in Oncology
interferon and immune responses
3.19
article

Oligoadenylate synthetase-like aggravated Newcastle disease virus–induced necroptosis in glioma cells

Yangkun Chen, Wei Han, Wenjing Ye, Fangwei Dai, L. Wang, Zecheng Yu, Wenhao Fu, Huazhong Ying, Sisi Chen, Yuxin Chen, Xianqiao Wei, Yutang Fu, Qin Yu, Ruirui Li, Yuheng Zhang, Yili Cai
article en
4 citations

Abstract

Our study demonstrates that NDV has cytolytic activity on glioma cells by inducing necroptosis. Additionally, targeting upregulation of OASL may provide a novel strategy to enhance necrotic apoptosis in glioma cells after NDV infection.

Frontiers in OncologyVol. 15
Hangzhou Medical College (CN)
Openalex Percentile: Top 8%
interferon and immune responses
3.19
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