Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept

Primary Sjögren's syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren's syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment.

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Journal
Frontiers in Immunology
Published
2025-04-11
DOI
https://doi.org/10.3389/fimmu.2025.1551094
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept

Jun Pang, Jian Shen, Hanqing Chu, Juan Chen et al.
Frontiers in Immunology
Salivary Gland Disorders and Functions
article

Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept

Jun Pang, Jian Shen, Hanqing Chu, Juan Chen, Fangfang Zhou
article en

Abstract

Primary Sjögren's syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren's syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment.

Frontiers in ImmunologyVol. 16
Ningbo No. 2 Hospital (CN), Ningbo University Affiliated Hospital (CN)
Natural Science Foundation of Ningbo
Good health and well-being
Openalex Percentile: Top 91%
Salivary Gland Disorders and Functions
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