Fecal microbiota transplantation alleviates lipopolysaccharide-induced osteoporosis by modulating gut microbiota and long non-coding RNA TUG1 expression
FMT can enhance osteoblast levels and improve bone structure by modulating the abundance of gut microbiota in OP mice (such as increasing Bacteroides and Lactobacillus populations) and promoting the expression of lncRNA <i>TUG1</i>, thereby alleviating LPS-induced OP.
Authors
- Jiachun Zheng
- Ruoyi Wang (ORCID: https://orcid.org/0009-0002-7995-0692)
- Hong‐Wei Gao (ORCID: https://orcid.org/0000-0003-1959-7452)
- Huizhi Chen
- Yao Lu (ORCID: https://orcid.org/0000-0002-2803-534X)
- Yifan Liu (ORCID: https://orcid.org/0000-0001-8529-3911)
- Pengcheng Ma (ORCID: https://orcid.org/0000-0002-1067-8021)
- Jing Zhao
- Bo Meng (ORCID: https://orcid.org/0000-0002-9396-2713)
- Weijie Yang (ORCID: https://orcid.org/0009-0006-0987-3969)
Institutions
- Shandong University (CN)
- Shandong Mental Health Center (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.3389/fcimb.2025.1535666
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94