Revisiting the use of CK7 and CK20 immunohistochemical stains in pathological diagnoses
Our results suggest that the coordinate expression of CK7 and CK20 is generally not helpful in arriving at the final diagnosis. Reducing unnecessary immunohistochemical stains will help mitigate the rising healthcare cost and preserve tissue for molecular testing.
Authors
- Jiaoti Huang (ORCID: https://orcid.org/0000-0003-1195-1998)
- Bangchen Wang (ORCID: https://orcid.org/0000-0002-0942-7858)
- Diana M. Cardona (ORCID: https://orcid.org/0000-0002-6877-2280)
Institutions
- Johns Hopkins University (US)
- Duke University (US)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1186/s13000-025-01638-x
- Citations
- 1
- Primary Topic
- Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.05