Fine-grained forecasting of COVID-19 trends at the county level in the United States
The novel coronavirus (COVID-19) pandemic has had a devastating global impact, profoundly affecting daily life, healthcare systems, and public health infrastructure. Despite the availability of treatments and vaccines, hospitalizations and deaths continue. Real-time surveillance of infection trends supports resource allocation and mitigation strategies, but reliable forecasting remains a challenge. While deep learning has advanced time-series forecasting, its effectiveness relies on large datasets, a significant obstacle given the pandemic's evolving nature. Most models use national or state-level data, limiting both dataset size and the granularity of insights. To address this, we propose the Fine-Grained Infection Forecast Network (FIGI-Net), a stacked bidirectional LSTM structure designed to leverage county-level data to produce daily forecasts up to two weeks in advance. FIGI-Net outperforms existing models, accurately predicting sudden changes such as new outbreaks or peaks, a capability many state-of-the-art models lack. This approach could enhance public health responses and outbreak preparedness.
Authors
- Junbong Jang (ORCID: https://orcid.org/0000-0001-9317-6520)
- Tzu‐Hsi Song (ORCID: https://orcid.org/0000-0002-3670-8970)
- Mauricio Santillana (ORCID: https://orcid.org/0000-0002-4206-418X)
- Kwonmoo Lee (ORCID: https://orcid.org/0000-0001-6838-7094)
- Xiang Pan (ORCID: https://orcid.org/0000-0002-7521-0702)
- Leonardo Clemente
Institutions
- Boston Children's Hospital (US)
- Northeastern University (US)
- Harvard University (US)
Publication Details
- Journal
- npj Digital Medicine
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1038/s41746-025-01606-1
- Citations
- 4
- Primary Topic
- COVID-19 epidemiological studies
- Type
- article
- Field-Weighted Citation Impact
- 5.47
Funders
- National Institutes of Health
- Centers for Disease Control and Prevention
- National Institute of General Medical Sciences