Identification of potential markers of elevated anticandidal activity of propolis extracts

The relatively low number of propolis samples collected in Poland exhibit considerable activity against Candida spp. Markers of elevated antifungal potential have been identified. Moreover, it has been proved, that only the composition of these compounds (not pure ingredients alone) is effective in the treatment of Candida spp. Mixtures of these ingredients can be considered as potential antifungal agents (artificial propolis). Moreover, UHPLC-DAD and UHPLC-QqTOF-MS methods of determining the chemical composition of EEPs have been optimized.