Unveiling Rarity: A Case Report on Clear Cell Carcinoma of Cervix

Clear cell carcinoma (CCC) of cervix is an extremely rare malignancy, accounting to only 4% of all adenocarcinoma of cervix.The majority of cases are related to in utero diethylstilbestrol (DES) exposure and it rarely occurs sporadic.The diagnosis of CCC of the uterine cervix is mainly established based on histopathological examination.Clear cell carcinomas of cervix have a greater tendency to recur and develop metastases in distant sites; hence, even after treatment long-term follow-up is necessary to detect local and distant relapse.We report one such rare case of CCC of cervix in a 62-year-old postmenopausal woman with history of per vaginal (PV) spotting and with no history of DES exposure.

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Publication Details

Journal
Journal of South Asian Federation of Obstetrics and Gynaecology
Published
2025-03-28
DOI
https://doi.org/10.5005/jp-journals-10006-2538
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Unveiling Rarity: A Case Report on Clear Cell Carcinoma of Cervix

Sushama Gurwale, Madhuri Singh, Mangesh M Londhe, Charusheela Gore et al.
Journal of South Asian Federation of Obstetrics and Gynaecology
Cervical Cancer and HPV Research
article

Unveiling Rarity: A Case Report on Clear Cell Carcinoma of Cervix

Sushama Gurwale, Madhuri Singh, Mangesh M Londhe, Charusheela Gore, Akshi Raj
article en

Abstract

Clear cell carcinoma (CCC) of cervix is an extremely rare malignancy, accounting to only 4% of all adenocarcinoma of cervix.The majority of cases are related to in utero diethylstilbestrol (DES) exposure and it rarely occurs sporadic.The diagnosis of CCC of the uterine cervix is mainly established based on histopathological examination.Clear cell carcinomas of cervix have a greater tendency to recur and develop metastases in distant sites; hence, even after treatment long-term follow-up is necessary to detect local and distant relapse.We report one such rare case of CCC of cervix in a 62-year-old postmenopausal woman with history of per vaginal (PV) spotting and with no history of DES exposure.

Journal of South Asian Federation of Obstetrics and GynaecologyVol. 17(1)
Openalex Percentile: Top 89%
Cervical Cancer and HPV Research
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