Persistent opioid use is associated with a shorter myeloma survival
We describe high rates of baseline COU in MM unrelated to bone disease. A number of patients started opioids during ASCT and were still taking them at 6-month follow-up visit. We demonstrate a negative association of 6-month COU on OS but not on PFS suggesting that opioid-related morbidity may play a role. These data highlight the need to test causality of opioid use on survival while simultaneously improving the management of pain in MM.
Authors
- Gregory S. Calip (ORCID: https://orcid.org/0000-0002-7744-3518)
- Craig C. Hofmeister (ORCID: https://orcid.org/0000-0003-4816-1607)
- Damiano Rondelli (ORCID: https://orcid.org/0000-0001-5243-401X)
- Zacharie Hamilton (ORCID: https://orcid.org/0009-0009-0904-7220)
- Kaily Kurzweil
- Karen Sweiss (ORCID: https://orcid.org/0000-0001-9559-0282)
- Chukwuemeka Uzoka
- E. D. Wolf
- Ana Maria Avila Rodriguez (ORCID: https://orcid.org/0000-0002-2918-8401)
- Pritesh Patel (ORCID: https://orcid.org/0000-0002-0313-2194)
- Douglas W. Sborov (ORCID: https://orcid.org/0000-0003-4268-2698)
- John G. Quigley (ORCID: https://orcid.org/0000-0003-3116-4545)
- Jaleel G. Sweis
- Elizabeth Ilo
- Lisa Kay Sharp (ORCID: https://orcid.org/0000-0002-7809-9042)
Institutions
- Emory University (US)
- Illinois College (US)
- American Association of Colleges of Pharmacy (US)
- Huntsman Cancer Institute (US)
- University of Illinois Chicago (US)
- Northwestern Memorial Hospital (US)
Publication Details
- Journal
- Supportive Care in Cancer
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1007/s00520-025-09407-8
- Citations
- 1
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.88