A rare example of humoral-related hypercalcaemia in pregnancy secondary to a uterine fibroid: a case report
Whilst uncommon in pregnancy, hypercalcaemia can lead to significant maternal and fetal morbidity. An important complication of hypercalcaemia is uncontrolled hypertension. This case outlines an example of refractory hypercalcaemia exacerbating an emerging hypertensive crisis. The proposed aetiology was parathyroid hormone-related protein (PTHrP)-mediated hypercalcaemia secondary to a necrotic uterine fibroid. We highlight how effective and prompt involvement of the Maternal Medicine Network and multidisciplinary team led to a successful pregnancy outcome.
Authors
- Carol Postlethwaite
- Karan Sampat
- Catherine Nelson-Piercy
- Chloe Gilkinson
- Hannah Beresford
Institutions
- King's College London (GB)
- South London and Maudsley NHS Foundation Trust (GB)
- Darent Valley Hospital (GB)
- Medway Maritime Hospital (GB)
- Kings Health Partners (GB)
- King's College Hospital (GB)
- Surrey and Sussex Healthcare NHS Trust (GB)
Publication Details
- Journal
- Obstetric Medicine
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1177/1753495x251326130
- Citations
- 1
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05