Nhận 2 ca lâm sàng hội chứng Budd-Chiari

This article describes 2 cases of patients who were diagnosed with Budd Chiari syndrome. A 56-yearold female patient, presenting with subacute Budd Chiari syndrome by ascites and elevated transaminase, she was successfully managed with anticoagulants and diuretics. A 39-year-old male patient suffer from chronic Budd Chiari with ascites, esophageal varices hemorrhage three times and cirrhosis. Liver transplant was offered for him but failed because of the familys financial inadequacy. Instead that he was management complication of cirrhosis and anticoagulants therapy. Thrombosis is the major cause of hepatic vein obstruction, both of these patients were found to have homozygous mutations in the gene group that increases the risk of thrombosis. For each patient, anticoagulation therapy, surgery to reduce portal hypertension or liver transplantation depends on the clinical condition of each patient.