Identification of the disulfidptosis-related key gene CD2AP as a potential biomarker and new therapeutic target for LUAD patients by comprehensive multi-omics analysis
This study highlights CD2AP's critical role in LUAD, particularly in immune microenvironment modulation, metabolic reprogramming, and drug response. CD2AP's high expression is linked to poor prognosis and may serve as a potential target for immunotherapy and drug response prediction.
Authors
- Zhiwu Lin (ORCID: https://orcid.org/0000-0002-7342-1805)
- Yuanwei Zhai
- Yanchun Yang (ORCID: https://orcid.org/0000-0001-6974-6175)
- Chuanqiang Dai
- Yang Yu (ORCID: https://orcid.org/0000-0002-5481-5382)
- Jiangang Fan
- Liang Wu (ORCID: https://orcid.org/0000-0001-6259-261X)
- Yang Gao (ORCID: https://orcid.org/0000-0002-9281-5965)
- Jiudong Jiang
- Jing Lv
- Rulin Li
Institutions
- Yantai Laiyang Central Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1007/s12672-025-02308-6
- Citations
- 2
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 1.59