Deep sequencing reveals distinct microRNA-mRNA signatures that differentiate pancreatic neuroendocrine tumor from non-diseased pancreas tissue
These novel miR-mRNA interaction networks identified dysregulated pathways not observed when assessing mRNA alone and provide a foundation for further investigation of their utility as diagnostic and predictive biomarkers.
Authors
- Natália Valková (ORCID: https://orcid.org/0000-0003-3898-7229)
- Neil Renwick (ORCID: https://orcid.org/0000-0001-6695-8236)
- Vladimír Palička (ORCID: https://orcid.org/0000-0001-7236-1647)
- Abulhameed Abdulhamed
- Evan D. Paul (ORCID: https://orcid.org/0000-0002-7011-8050)
- Pavol Čekan (ORCID: https://orcid.org/0000-0001-8806-9958)
- Manish Gala (ORCID: https://orcid.org/0000-0002-3126-0783)
- Silvia Bendíková
- Natália Matyašovská
Institutions
- University Hospital Hradec Králové (CZ)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-11
- DOI
- https://doi.org/10.1186/s12885-025-14043-w
- Citations
- 4
- Primary Topic
- Neuroendocrine Tumor Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- Univerzita Karlova v Praze
- Grantová Agentura, Univerzita Karlova
- Government of Ontario