Assessment of the Toxicity of Free and PLGA-Encapsulated Phospholipase A2 CB: An In Vitro Approach
It was concluded that using the phospholipase component of the toxin in a polymeric-controlled delivery and targeted system may be an alternative solution to the issues in advancing this bioactive molecule in clinical-oncological studies. However, further studies are still being conducted for targeted treatment involving this nanotechnological approach.
Authors
- V. Goncalves (ORCID: https://orcid.org/0000-0003-4801-7189)
- Andreimar M. Soares (ORCID: https://orcid.org/0000-0003-1032-2188)
- Vicente Candela‐Noguera (ORCID: https://orcid.org/0000-0001-5310-8443)
- Marlos de Medeiros Chaves (ORCID: https://orcid.org/0000-0001-5513-5963)
- Javier Martínez-Latorre (ORCID: https://orcid.org/0000-0001-5421-5371)
- João Pedro Viana Rodrigues (ORCID: https://orcid.org/0000-0002-0549-6215)
- Alba García‐Fernández (ORCID: https://orcid.org/0000-0002-8416-1674)
- Paula M. Soriano‐Teruel
- Cláudia Pessoa (ORCID: https://orcid.org/0000-0002-4344-4336)
- Gabriel Acácio de Moura (ORCID: https://orcid.org/0000-0002-1515-6951)
- Ramón Martínez‐Máñez (ORCID: https://orcid.org/0000-0001-5873-9674)
- Roberto Nicolete (ORCID: https://orcid.org/0000-0003-0471-3975)
- Anderson Maciel de Lima
Institutions
- Universidade Estadual do Ceará (BR)
- Universidade Federal do Ceará (BR)
- Centro de Investigacion Principe Felipe (ES)
- Fundação Oswaldo Cruz (BR)
- Universitat Politècnica de València (ES)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-04-11
- DOI
- https://doi.org/10.2174/0109298673274499250327053516
- Citations
- 1
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.82