A Case of Thrombocytopenia Induced by Tirofiban after Stent-Assisted Embolization for Aneurysm

1例左侧后交通动脉瘤破裂伴蛛网膜下腔出血患者急诊行全脑血管造影术 + 颅内动脉瘤支架辅助栓塞术术中予盐酸替罗非班后出现极重度血小板减少症，最低血小板计数为1 × 109/L。在停用该药后及对症治疗后血小板逐渐恢复，继续予以阿司匹林肠溶片、硫酸氢氯吡格雷预防血栓，最终好转出院。A patient with a ruptured left posterior communicating artery aneurysm accompanied by subarachnoid hemorrhage underwent emergency cerebral angiography and intracranial aneurysm stent-assisted coiling. During the procedure, administration of tirofiban hydrochloride induced profound thrombocytopenia, with the lowest platelet count dropping to 1 × 109/L. Following discontinuation of the medication and symptomatic treatment, platelet levels gradually recovered. Thrombosis prophylaxis was maintained with enteric-coated aspirin tablets and clopidogrel bisulfate. The patient ultimately improved and was discharged.