Reciprocal regulation between B lymphoma Mo-MLV insertion region 1 homolog and type I insulin-like growth factor receptor in pemetrexed-resistant lung cancer cells
A novel reciprocal regulatory relationship between IGF-1R and BMI1 has been identified in lung cancer cells, suggesting potential therapeutic strategies to combat pemetrexed resistance in lung cancer patients.
Authors
- Gwo‐Tarng Sheu (ORCID: https://orcid.org/0000-0002-1299-3375)
- Huan‐Ting Shen
- Bing‐Yen Wang (ORCID: https://orcid.org/0000-0002-9620-3085)
- Peng‐Ju Chien (ORCID: https://orcid.org/0000-0003-0278-0496)
- Wen‐Wei Chang (ORCID: https://orcid.org/0000-0003-2283-1377)
Institutions
- National Chung Hsing University (TW)
- Taipei Tzu Chi Hospital (TW)
- Chung Shan Medical University Hospital (TW)
- Changhua Christian Hospital (TW)
- Chung Shan Medical University (TW)
Publication Details
- Journal
- Tzu Chi Medical Journal
- Published
- 2025-04-11
- DOI
- https://doi.org/10.4103/tcmj.tcmj_288_24
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00