Correlation of N-telopeptide of type 1 collagen and C-telopeptide of type 1 collagen in Iraqi women with breast cancer

Among the most common cancers worldwide is breast cancer. It is a varied sickness that is the leading cause of cancer-related mortality in females. Prognostic biomarkers—N-telopeptide of type 1 collagen and C-telopeptide of type 1 collagen—are being researched more and more to help with management, even though more research is needed to improve specificity and determine the actual therapeutic use of particular indications. The ELISA method was utilized to measure the levels of both CTX-1 and NTX-1. At the Oncology Teaching Hospital in the Medical City of Baghdad, these markers were examined in the serum of ninety women, forty of whom were healths and fifty of whom had the disease. The women's ages ranged from 40 to 60 years old, statistical research was significantly increased NTX-1 levels were found. CTX-1 did not reveal any discernible variation in the patient's group. The best marker for breast cancer diagnosis, according to a Receiver Operating Characteristic curve analysis, is NTX-1. Our results indicate that serum NTx has potential applications as a prognostic biomarker for bone metastases of several cancers, including breast cancer in Iraqi women.