The people behind the papers – Ramya Ranganathan and Andrea Streit

The transcription factor Six1 and its co-factor, Eya1, regulate inner ear development in vertebrates, and loss of Six1 or Eya1 causes developmental differences. In their study, Andrea Streit and colleagues find new gene targets of Six1 that overlap with known human deafness loci in the early inner ear. To know more about their work, we spoke to the first author, Ramya Ranganathan, and the corresponding author, Andrea Streit, Professor of Developmental Neurobiology and Head of the Centre for Craniofacial & Regenerative Biology at King's College London, UK.