Risky decision-making in dementia: Exploring neural correlates and related clinical symptoms
Our findings highlight the heterogeneous nature of affective decision-making deficits in dementia and uncover important links between BART performance, symptoms of disinhibition and apathy, and orbitofrontal cortex atrophy. Greater understanding of these symptom profiles and underlying neurocognitive mechanisms may help to inform potential management strategies for impaired affective decision-making in dementia.
Authors
- Grace Wei (ORCID: https://orcid.org/0000-0001-5378-920X)
- Melissa A. Day (ORCID: https://orcid.org/0000-0003-1967-4884)
- James R. Burrell (ORCID: https://orcid.org/0000-0001-9638-2768)
- Stephanie Wong (ORCID: https://orcid.org/0000-0002-0990-5039)
- David Foxe (ORCID: https://orcid.org/0000-0003-0299-3344)
- Olivier Piguet (ORCID: https://orcid.org/0000-0002-6696-1440)
- Fiona Kumfor (ORCID: https://orcid.org/0000-0002-3208-075X)
Institutions
- The University of Sydney (AU)
- Flinders University (AU)
Publication Details
- Journal
- Cognitive Affective & Behavioral Neuroscience
- Published
- 2025-04-11
- DOI
- https://doi.org/10.3758/s13415-025-01291-3
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Flinders University