Medical Multimodal Model Stealing Attacks via Adversarial Domain Alignment

Medical multimodal large language models (MLLMs) are becoming an instrumental part of healthcare systems, assisting medical personnel with decision making and results analysis. Models for radiology report generation are able to interpret medical imagery, thus reducing the workload of radiologists. As medical data is scarce and protected by privacy regulations, medical MLLMs represent valuable intellectual property. However, these assets are potentially vulnerable to model stealing, where attackers aim to replicate their functionality via black-box access. So far, model stealing for the medical domain has focused on image classification; however, existing attacks are not effective against MLLMs. In this paper, we introduce Adversarial Domain Alignment (ADA-Steal), the first stealing attack against medical MLLMs. ADA-Steal relies on natural images, which are public and widely available, as opposed to their medical counterparts. We show that data augmentation with adversarial noise is sufficient to overcome the data distribution gap between natural images and the domain-specific distribution of the victim MLLM. Experiments on the IU X-RAY and MIMIC-CXR radiology datasets demonstrate that Adversarial Domain Alignment enables attackers to steal the medical MLLM without any access to medical data.

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Publication Details

Journal
Proceedings of the AAAI Conference on Artificial Intelligence
Published
2025-04-11
DOI
https://doi.org/10.1609/aaai.v39i7.32734
Citations
4
Primary Topic
Adversarial Robustness in Machine Learning
Type
article
Field-Weighted Citation Impact
3.55

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Medical Multimodal Model Stealing Attacks via Adversarial Domain Alignment

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Proceedings of the AAAI Conference on Artificial Intelligence
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article

Medical Multimodal Model Stealing Attacks via Adversarial Domain Alignment

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article en
4 citations

Abstract

Medical multimodal large language models (MLLMs) are becoming an instrumental part of healthcare systems, assisting medical personnel with decision making and results analysis. Models for radiology report generation are able to interpret medical imagery, thus reducing the workload of radiologists. As medical data is scarce and protected by privacy regulations, medical MLLMs represent valuable intellectual property. However, these assets are potentially vulnerable to model stealing, where attackers aim to replicate their functionality via black-box access. So far, model stealing for the medical domain has focused on image classification; however, existing attacks are not effective against MLLMs. In this paper, we introduce Adversarial Domain Alignment (ADA-Steal), the first stealing attack against medical MLLMs. ADA-Steal relies on natural images, which are public and widely available, as opposed to their medical counterparts. We show that data augmentation with adversarial noise is sufficient to overcome the data distribution gap between natural images and the domain-specific distribution of the victim MLLM. Experiments on the IU X-RAY and MIMIC-CXR radiology datasets demonstrate that Adversarial Domain Alignment enables attackers to steal the medical MLLM without any access to medical data.

Proceedings of the AAAI Conference on Artificial IntelligenceVol. 39(7)
German Research Centre for Artificial Intelligence (DE), Helmholtz Center for Information Security (DE), Institut de Chirurgie Guidée par l'Image (FR), Technical University of Munich (DE), Université de Strasbourg (FR)
European Commission, Grand Équipement National De Calcul Intensif
Openalex Percentile: Top 6%
Adversarial Robustness in Machine Learning
3.55
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