Idiopathic Granulomatous Appendicitis: A Case Report and Review of the Literature

Idiopathic granulomatous appendicitis (IGA) is a rare condition that clinically presents similar to acute appendicitis, with symptoms such as abdominal pain, fever, and anorexia. We report a case of a 30-year-old postpartum female who presented with symptoms of acute appendicitis. Imaging revealed a thickened appendix, and laparoscopic appendectomy was performed. Intraoperative findings led to conversion to laparotomy with ileocolic resection. Histopathology confirmed granulomatous appendicitis with focal suppuration and no evidence of Crohn's disease or infection. IGA is diagnosed by excluding other infectious or non-infectious causes, and appendectomy is the treatment of choice, with a favorable prognosis. The condition requires careful pathological evaluation to avoid unnecessary extensive surgery.

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Publication Details

Journal
Cureus
Published
2025-04-11
DOI
https://doi.org/10.7759/cureus.82081
Primary Topic
Appendicitis Diagnosis and Management
Type
article
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0.00
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article

Idiopathic Granulomatous Appendicitis: A Case Report and Review of the Literature

Isaac Theerman, Jason Beckermann, Amir Awad
Cureus
Appendicitis Diagnosis and Management
article

Idiopathic Granulomatous Appendicitis: A Case Report and Review of the Literature

Isaac Theerman, Jason Beckermann, Amir Awad
article en

Abstract

Idiopathic granulomatous appendicitis (IGA) is a rare condition that clinically presents similar to acute appendicitis, with symptoms such as abdominal pain, fever, and anorexia. We report a case of a 30-year-old postpartum female who presented with symptoms of acute appendicitis. Imaging revealed a thickened appendix, and laparoscopic appendectomy was performed. Intraoperative findings led to conversion to laparotomy with ileocolic resection. Histopathology confirmed granulomatous appendicitis with focal suppuration and no evidence of Crohn's disease or infection. IGA is diagnosed by excluding other infectious or non-infectious causes, and appendectomy is the treatment of choice, with a favorable prognosis. The condition requires careful pathological evaluation to avoid unnecessary extensive surgery.

CureusVol. 17(4)
Mayo Clinic Health System (US)
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Openalex Percentile: Top 87%
Appendicitis Diagnosis and Management
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