Impact of Subsequent Treatment on Clinical Outcomes in Patients with EGFR-Mutant Non-Small Cell Lung Cancer Transformed to Small-Cell Lung Cancer
In patients with SCLC transformed from advanced NSCLC after EGFR-TKI treatment, adding immunotherapy and EGFR-TKI to CT improved DCR and showed trends in ORR and PFS, but did not provide an OS benefit. More prospective studies with varied therapeutic approaches are needed to confirm these findings.
Authors
- Yu-Chi Chiu (ORCID: https://orcid.org/0000-0001-7636-2073)
- Po‐Wei Hu (ORCID: https://orcid.org/0000-0002-4784-6324)
- Yu‐Feng Wei (ORCID: https://orcid.org/0000-0002-6380-3527)
- Chung‐Yu Chen (ORCID: https://orcid.org/0000-0001-9002-7255)
- Shih‐Chieh Chang (ORCID: https://orcid.org/0000-0002-5481-9877)
- How‐Wen Ko (ORCID: https://orcid.org/0000-0002-6415-2965)
- Ching-Yi Chen (ORCID: https://orcid.org/0000-0002-3320-1680)
- Cheng‐Yu Chang (ORCID: https://orcid.org/0000-0002-7196-3504)
Institutions
- National Yang Ming Chiao Tung University (TW)
- E-Da Hospital (TW)
- Far Eastern Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
- Ministry of Health and Welfare (TW)
- National Taiwan University Hospital (TW)
- National Yunlin University of Science and Technology (TW)
- I-Shou University (TW)
- Yuan Ze University (TW)
Publication Details
- Journal
- Lung Cancer Targets and Therapy
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/lctt.s516527
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52