ANALYSIS OF THE EFFICIENCY OF PRESERVING THE VIABILITY OF THE RABIES VIRUS USING A TRANSPORT MEDIUM

The article is devoted to the study of the efficiency of preserving the viability of the rabies virus using a specialized transport medium. Rabies is a dangerous zoonotic disease, and maintaining the stability of the virus during transportation is critical for diagnostics, vaccine development, and scientific research. The aim of the work was to assess the effect of the composition of the transport medium on the stability of viral particles and their ability to replicate after transportation. The results of the study showed that the use of a specialized transport medium significantly increases the stability of the rabies virus. Samples transported in an optimized medium demonstrated higher viability and replication capacity compared to control samples transported under standard conditions. This confirms that the composition of the transport medium plays a key role in maintaining the integrity of viral particles. The study used serology and virology methods. The experiments included modeling of transportation conditions, such as temperature changes, followed by an analysis of the safety of viral particles. The transport medium was optimized taking into account pH, osmotic pressure, and the presence of stabilizing additives. The practical significance of the work lies in the possibility of improving the conditions for transporting the rabies virus, which is especially important for remote regions with limited resources. The developed transport medium can be used to deliver viral samples to diagnostic laboratories, which will increase the accuracy of diagnostics and accelerate the development of new drugs. In addition, the proposed method can be adapted for transporting other viruses, which expands its application in virology and biotechnology.

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Publication Details

Journal
3i intellect idea innovation - интеллект идея инновация
Published
2025-01-01
DOI
https://doi.org/10.52269//22266070_2025_1_72
Primary Topic
Rabies epidemiology and control
Type
article
Field-Weighted Citation Impact
0.00
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article

ANALYSIS OF THE EFFICIENCY OF PRESERVING THE VIABILITY OF THE RABIES VIRUS USING A TRANSPORT MEDIUM

Maxat Berdikulov, Abylay Sansyzbay, Yerkin Krykbayev, Dauren Mukhanov
3i intellect idea innovation - интеллект идея инновация
Rabies epidemiology and control
article

ANALYSIS OF THE EFFICIENCY OF PRESERVING THE VIABILITY OF THE RABIES VIRUS USING A TRANSPORT MEDIUM

Maxat Berdikulov, Abylay Sansyzbay, Yerkin Krykbayev, Dauren Mukhanov
article en

Abstract

The article is devoted to the study of the efficiency of preserving the viability of the rabies virus using a specialized transport medium. Rabies is a dangerous zoonotic disease, and maintaining the stability of the virus during transportation is critical for diagnostics, vaccine development, and scientific research. The aim of the work was to assess the effect of the composition of the transport medium on the stability of viral particles and their ability to replicate after transportation. The results of the study showed that the use of a specialized transport medium significantly increases the stability of the rabies virus. Samples transported in an optimized medium demonstrated higher viability and replication capacity compared to control samples transported under standard conditions. This confirms that the composition of the transport medium plays a key role in maintaining the integrity of viral particles. The study used serology and virology methods. The experiments included modeling of transportation conditions, such as temperature changes, followed by an analysis of the safety of viral particles. The transport medium was optimized taking into account pH, osmotic pressure, and the presence of stabilizing additives. The practical significance of the work lies in the possibility of improving the conditions for transporting the rabies virus, which is especially important for remote regions with limited resources. The developed transport medium can be used to deliver viral samples to diagnostic laboratories, which will increase the accuracy of diagnostics and accelerate the development of new drugs. In addition, the proposed method can be adapted for transporting other viruses, which expands its application in virology and biotechnology.

3i intellect idea innovation - интеллект идея инновацияVol. 1
Copiah-Lincoln Community College (US)
Openalex Percentile: Top 92%
Rabies epidemiology and control
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