Comparative Analysis of Hypertension Medications in Saudi Arabia: Evaluating Efficacy and Blood Pressure Reduction for Patients with Hypertension Following Up in PHCs in Makkah, Saudi Arabia, 2023

Background: Hypertension poses a substantial public health concern and continues to be a pivotal area of exploration due to its extensive prevalence and its role as a primary risk factor for cardiovascular diseases. Aim: to assess and compare the effectiveness of various antihypertensive medications in controlling or reducing blood pressure measurements among Saudi hypertensive patients. Methodology: Analytical cross-sectional study based on patient health information system data. Results: This study included 6,242 participants with high BP. ACE, ARB, and CCB significantly reduced MAP over time, with males experiencing more significant reductions than females. Conclusion: This study highlights the superior efficacy of ACE inhibitors, ARB, and CCB in reducing MAP over time, while BB and diuretics had a limited impact.