Antioxidant, antimicrobial, enzyme inhibitory and cytotoxic effect of Taverniera couneifolia plant mediated Silver nanoparticles
This study was conducted to evaluate antioxidant, anticancer, enzyme inhibitory and antimicrobial potential of methanolic extract and AgNPs of T. couneifolia. The (DPPH) 1,1-diphenyl-2-picrylhydrazyl, (ABTS) 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid), metal chelating, phosphomolybdenum, hydrogen peroxide scavenging and (FRAP) ferric reducing antioxidant power activities, antibacterial potential against Klebsiella pneumonia, Escretia coli, Acetobacter, Staphylococcus aureus and Staphylococcus epidermidis, antifungal against Aspergillus niger and Aspergillus flavus and enzyme inhibitory including alpha amylase and acetyl cholinesterase were used to evaluate the methanolic extract and the synthesized AgNPs' antioxidant potential. T AgNPs displayed the highest enzyme and radical scavenging capabilities in comparison to the plant extract. Additionally, the BSL test was used to measure the cytotoxicity activity. Our findings unequivocally demonstrated that biosynthesized AgNPs had antimicrobial, antioxidant, enzyme inhibitory and cytotoxic action and reduced the growth capability.
Authors
- Ammara Khan
- Zamarud Shah (ORCID: https://orcid.org/0000-0001-6217-264X)
- Ghulam Mujtaba Shah (ORCID: https://orcid.org/0000-0002-9525-610X)
- Mati Ullah (ORCID: https://orcid.org/0000-0003-2289-1505)
- Muhammad Nisar Ul Haq (ORCID: https://orcid.org/0000-0002-8361-4045)
- Feroz Khan (ORCID: https://orcid.org/0000-0002-7318-4918)
- Rahmat Ali Khan (ORCID: https://orcid.org/0000-0003-1660-0396)
- Ihsan Ullah (ORCID: https://orcid.org/0000-0001-5655-4975)
- K. Rahman (ORCID: https://orcid.org/0009-0004-5982-0764)
- Wahid Ullah (ORCID: https://orcid.org/0009-0006-5696-3131)
- Hajra Afeera Hamid
Institutions
- University of Science and Technology Bannu (PK)
Publication Details
- Journal
- Liaquat Medical Research Journal
- Published
- 2024-12-31
- DOI
- https://doi.org/10.38106/lmrj.2024.6.4-06
- Primary Topic
- Medicinal Plant Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00