A Rare Case of Pituicytoma During Pregnancy

Pituicytomas are rare benign sellar tumors that originate in the neurohypophysis. We report the first case of a pituicytoma during pregnancy, causing headaches and bilateral temporal visual field defects. A 32-year-old woman at 16 weeks of gestation was admitted to our hospital for headaches and progressively worsening visual impairment. Cranial magnetic resonance imaging (MRI) revealed a sellar lesion that was resected via a neuroendoscopic endonasal-transsphenoid approach. Pathology revealed a pituicytoma with positive progesterone receptor expression. After cerebrospinal fluid (CSF) leakage repair and anti-infective therapy, the patient recovered well and finally gave birth to a healthy child. This is the first case of pituicytoma during pregnancy reported. Pregnancy may have a contributing effect on the progression of progesterone receptor-positive pituicytomas. Surgical intervention, when performed with appropriate perioperative management, can effectively alleviate mass effects caused by pituicytomas in pregnant women while maintaining the safety of the fetus.

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Publication Details

Journal
JCEM Case Reports
Published
2025-03-27
DOI
https://doi.org/10.1210/jcemcr/luaf071
Citations
2
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
2.59

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article

A Rare Case of Pituicytoma During Pregnancy

Hao Tang, Shaojian Lin, Bo Zhang, Zhe Wu et al.
2 citations
JCEM Case Reports
Pituitary Gland Disorders and Treatments
2.59
article

A Rare Case of Pituicytoma During Pregnancy

Hao Tang, Shaojian Lin, Bo Zhang, Zhe Wu, Jianli Wu
article en
2 citations

Abstract

Pituicytomas are rare benign sellar tumors that originate in the neurohypophysis. We report the first case of a pituicytoma during pregnancy, causing headaches and bilateral temporal visual field defects. A 32-year-old woman at 16 weeks of gestation was admitted to our hospital for headaches and progressively worsening visual impairment. Cranial magnetic resonance imaging (MRI) revealed a sellar lesion that was resected via a neuroendoscopic endonasal-transsphenoid approach. Pathology revealed a pituicytoma with positive progesterone receptor expression. After cerebrospinal fluid (CSF) leakage repair and anti-infective therapy, the patient recovered well and finally gave birth to a healthy child. This is the first case of pituicytoma during pregnancy reported. Pregnancy may have a contributing effect on the progression of progesterone receptor-positive pituicytomas. Surgical intervention, when performed with appropriate perioperative management, can effectively alleviate mass effects caused by pituicytomas in pregnant women while maintaining the safety of the fetus.

JCEM Case ReportsVol. 3(5)
Shanghai Jiao Tong University (CN), Ruijin Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 11%
Pituitary Gland Disorders and Treatments
2.59
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