Efficient detection of <sup>1</sup>H, <sup>15</sup>N correlations in hydrogen bonded low molecular catalyst–substrate intermediates without selective <sup>15</sup>N-labelling
To date, SOFAST approaches have generally been limited to biomolecules. We present the applicability of SOFAST-HMQC techniques to small molecules in the slow-tumbling regime offering a time-efficient characterization of catalyst substrate hydrogen bonds with nitrogen at natural abundance. This extends NMR access to a broader range of catalyst substrate combinations.
Authors
- Julian Ilgen (ORCID: https://orcid.org/0000-0003-4130-4708)
- Ruth M. Gschwind (ORCID: https://orcid.org/0000-0003-3052-0077)
- Christian Scholtes
Institutions
- University of Regensburg (DE)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00537j
- Primary Topic
- Mass Spectrometry Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft