Treatment Outcomes for Drug-Resistant Tuberculosis Patients on Bedaquiline-Based Regimens in a Mostly Rural South Africa

In South Africa's mostly rural areas, BDQ-containing regimens proved to be more effective in enhancing treatment outcomes and lowering mortality rates for DR-TB patients. But to keep TB treatment regimens successful, comprehensive drug susceptibility testing and ongoing surveillance are required considering the growing concern over BDQ resistance.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-04-01
DOI
https://doi.org/10.2147/idr.s502302
Citations
3
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
4.19
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article

Treatment Outcomes for Drug-Resistant Tuberculosis Patients on Bedaquiline-Based Regimens in a Mostly Rural South Africa

Molebogeng Ruth Lekalakala-Mokaba, Kabelo Gabriel Kaapu, Ivy Rukasha, Sarah M. Fortune
3 citations
Infection and Drug Resistance
Tuberculosis Research and Epidemiology
4.19
article

Treatment Outcomes for Drug-Resistant Tuberculosis Patients on Bedaquiline-Based Regimens in a Mostly Rural South Africa

Molebogeng Ruth Lekalakala-Mokaba, Kabelo Gabriel Kaapu, Ivy Rukasha, Sarah M. Fortune
article en
3 citations

Abstract

In South Africa's mostly rural areas, BDQ-containing regimens proved to be more effective in enhancing treatment outcomes and lowering mortality rates for DR-TB patients. But to keep TB treatment regimens successful, comprehensive drug susceptibility testing and ongoing surveillance are required considering the growing concern over BDQ resistance.

Infection and Drug ResistanceVol. Volume 18
National Health Laboratory Service (ZA), Massachusetts Department of Public Health (US), Harvard University (US), University of Limpopo (ZA)
Good health and well-being
Openalex Percentile: Top 7%
Tuberculosis Research and Epidemiology
4.19
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